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BAY 19-8004  - Lirimilast

CAS 329306-27-6

C17H12Cl2N2O6S  MW 443.26

Purity: >98%

 

 

 

 

Ordering Information:

 

Cat. No. Axon 1178     Prime Source

 

Qty1: 5 mg (research sample) / €135  $176

 

Qty2: 25 mg (research sample) / inquire

 

Qty3: on request contract research synthesis

 

Send enquiry to: order@axonmedchem.com

or by fax to: +31-50-3600390.

 

Contact us for payment and tech support.

 

Biological Activity:

 

Selective inhibitor of phosphodiesterase-4 (PDE4)

 

References: online 1, 2, 3

 

D.C. Grootendorst et al. Efficacy of the novel phosphodiesterase-4 inhibitor BAY 19-8004 on lung function and airway inflammation in asthma and chronic
obstructive pulmonary disease (COPD). Pulmonary Pharmacol. Ther. 16 (2003) 341–347.

 

P. Norman. PDE4 inhibitors: sustained patenting activity as leading drugs near the market. Exp. Opin. Ther. Pat.2000, 10, 9, 1415-1427.

 

D.C. Grootendorst, K.F. Rabe. Selective phosphodiesterase inhibitors for the treatment of asthma and chronic obstructive pulmonary disease. Mechanisms in allergy and adult asthma. Cur. Opin. Aller. Clin. Immunol. 2002, 2(1), 61-67.

 

 

Chemical Name: Methanesulfonic acid 2-(2,4-dichloro-benzoyl)-3-ureido-benzofuran-6-yl ester

 

BAY 19-8004 - Lirimilast | PDE4 inhibitor | Axon Medchem | Axon 1178 | Bay19-8004 - BAY-198004

 

Axon Ligands TM - Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.

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Axon Ligands In The Field:

 

Lirimilast | PDE4 inhibitor

Cilomilast | PDE4 inhibitor

L 454560 | PDE4 inhibitor

Rolipram | PDE4 inhibitor

R-(-)-Rolipram | PDE4 inhibitor

 

Olprinone | PDE3 inhibitor

Parogrelil | PDE3 inhibitor

Zardaverine | PDE3/4 inhibitor

 

PDE5 inhibitor | Axon 1709