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TEI-6720 - Febuxostat

CAS 144060-53-7

C16H16N2O3S  MW 316.38

Purity: >98%

Soluble in DMSO and EtOH

Ordering Information:

Cat. No. Axon 1175

Qty1: 10 mg / €115  $150

Promotion: 2 x 10 mg @ €160  $208

Qty2: 50 mg / €405  $527

Promotion: 2 x 50 mg @ €560  $728

Qty3: on request

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Biological Activity:   A non-puriine selective xanthine oxidase (XO) inhibitor   References: online ref 1   T Yamamoto et al. Effect of TEI-6720, a xanthine oxidase inhibitor, on the nucleoside transport in the lung cancer cell line A549. Pharmacology 2000, 60(1), 34-40.   J Biol Chem. 2003 Jan 17;278(3):1848-55. Epub 2002 Nov 5. K Okamoto et al. An extremely potent inhibitor of xanthine oxidoreductase. Crystal structure of the enzyme-inhibitor complex and mechanism of inhibition. J. Biol. Chem. 2003, 278(3), 1848-1855. [online]       Chemical Name:2-(3-Cyano-4-isobutoxy-phenyl)-4-methyl-thiazole-5-carboxylic acid

TEI-6720 | Xanthine oxidase inhibitor | Axon Medchem | Axon 1175 | TEI6720 - Febuxostat

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Axon Ligands In The Field:

TEI-6720 | XO inhibitor

Y-700 | XO inhibitor