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Olprinone - Loprinone

 

 

CAS 106730-54-5

119615-63-3 (HCl)

C14H10N4O  MW 286.72

Purity: >98%

 

 

 

 

Ordering Information:

 

Cat. No. Axon 1168

 

Qty1: 10 mg / €119  $155

 

Qty2: 50 mg / inquire

 

Qty3: on request

 

Send enquiry to: order@axonmedchem.com

or by fax to: +31-50-3600390.

 

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Biological Activity:

 

Selective PDE III (PDE3) inhibitor; cardiotonic agent; with positive inotropic and vasodilating effects; as a therapeutic agent for acute heart failure

 

References:

 

N Enomoto et al. The Phosphodiesterase III Inhibitor Olprinone Decreases Sensitivity of Rat Kupffer Cells to Endotoxin. Alcohol. Clin. Exp. Res. 2004, 28, 45S-147S.

 

 

Chemical Name: 5-Imidazo[1,2-a]pyridin-6-yl-6-methyl-2-oxo-1,2-dihydro-pyridine-3-carbonitrile

Olprinone | PDE3 inhibitor | Axon Medchem | Loprinone | Axon 1168

 

Axon Ligands TM - Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.

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Axon Ligands In The Field:

 

BAY 19-8004 | PDE4 inhibitor

Cilomilast | PDE4 inhibitor

L 454560 | PDE4 inhibitor

Rolipram | PDE4 inhibitor

R-(-)-Rolipram | PDE4 inhibitor

 

Olprinone | PDE3 inhibitor

Parogrelil | PDE3 inhibitor

Zardaverine | PDE3/4 inhibitor

 

PDE5 inhibitor | Axon 1709