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Biological Activity:
Selective PDE III (PDE3) inhibitor; cardiotonic agent; with positive inotropic and vasodilating effects; as a therapeutic agent for acute heart failure
References:
N Enomoto et al. The Phosphodiesterase III Inhibitor Olprinone Decreases Sensitivity of Rat Kupffer Cells to Endotoxin. Alcohol. Clin. Exp. Res. 2004, 28, 45S-147S.
Chemical Name: 5-Imidazo[1,2-a]pyridin-6-yl-6-methyl-2-oxo-1,2-dihydro-pyridine-3-carbonitrile
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| Olprinone | PDE3 inhibitor | Axon Medchem | Loprinone | Axon 1168 |
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Axon Ligands TM - Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis. |
axonmedchem.com © 2012 |
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Axon Ligands In The Field:
BAY 19-8004 | PDE4 inhibitor
Cilomilast | PDE4 inhibitor
L 454560 | PDE4 inhibitor
Rolipram | PDE4 inhibitor
R-(-)-Rolipram | PDE4 inhibitor
Olprinone | PDE3 inhibitor
Parogrelil | PDE3 inhibitor
Zardaverine | PDE3/4 inhibitor
PDE5 inhibitor | Axon 1709 |