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SR 48692 - Meclinertant

CAS 146362-70-1

C32H31ClN4O5  MW 587.08

Purity: 99%

Ordering Information:

Cat. No. Axon 1164    Prime Source Promotion

Qty1: 2 mg (research sample) / €105  $137

Qty2: 5 mg (research sample) / €155  $202

Promotion: 2 x 5 mg @ €240  $312

Qty3: 25 mg (research sample) / €580  $754

Promotion: 2 x 25 mg @ €840  $1092

Qty4: on request

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Biological Activity:   An orally active, non-peptide, high affinity neurotensin (NT1) receptor (NTSR1) antagonist   References: online ref 1, 2, 3   Horger et al. Preexposure to, but Not Cotreatment with, the Neurotensin Antagonist SR 48692 Delays the Development of Cocaine Sensitization. Neuropsychopharmacology 1994, 11, 215-222.   Croci et al. Negative modulation of nitric oxide production by neurotensin as a putative mechanism of the diuretic action of SR 48692 in rats. Br. J. Pharmacol. 1997, 120, 1312–1318.     Chemical Name: 2-{[1-(7-Chloro-quinolin-4-yl)-5-(2,6-dimethoxy-phenyl)-1H-pyrazole-3-carbonyl]-amino}-adamantane-2-carboxylic acid

SR 48692 | Neurotensin antagonist | Axon Medchem | Axon 1164 | SR48692 - Meclinertant - Reminertant

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Axon Ligands In The Field:

SR 48692 | NT antagonist

SR 142948 | NT antagonist

Axon Ligands ^TM    

Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.