Celiprolol | beta 1 Blocker | Axon Ligands | Axon Medchem

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Celiprolol

CAS 57470-78-7 (HCl)

56980-93-9 (free base)

C20H33N3O4.HCl MW 415.96

Purity: >98%

Ordering Information:

Cat. No. Axon 1159

Qty1: 10 mg / 135 $176

Qty2: 50 mg / 375 $488

Qty3: on request

Send enquiry to: order@axonmedchem.com

or by fax to: +31-50-3600390.

Biological Activity:

A ß-blocker possessing strong ß₁-adrenoceptor antagonist and mild ß₂-agonist properties.

References: online 1, 2

Y Liao et al. Celiprolol, A Vasodilatory ß-Blocker, Inhibits Pressure OverloadInduced Cardiac Hypertrophy and Prevents the Transition to Heart Failure via Nitric OxideDependent Mechanisms in Mice. Circulation. 2004, 110, 692-699.

FS Caruso et al. Effect of celiprolol, a new beta 1-alpha 2 blocker, on the cardiovascular response to exercise. J. Clin. Pharmacol. 1986; 26, 32-38.

M Cazzola et al. Comparison of the Effects of Single Oral Doses of Nebivolol and Celiprolol on Airways in Patients With Mild Asthma. Chest. 2000, 118, 1322-1326.

Chemical Name: 3-[3-Acetyl-4-(3-tert-butylamino-2-hydroxy-propoxy)-phenyl]-1,1-diethyl-urea hydrochloride

Celiprolol | beta 1 Blocker | Axon Medchem | Axon 1159

axonmedchem.com Š 2012

Axon Ligands In The Field:

Celiprolol | β blocker

Timolol | β blocker

Axon Ligands ^TM

Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.