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Ifenprodil

 

 

CAS 23210-56-2

23210-58-4 (tartrate)

C21H27NO2  MW 325.45

Purity: >98%

 

 

 

 

Ordering Information:

 

Cat. No. Axon 1156

 

Qty1: 10 mg / €55  $72

 

Qty2: 50 mg / €215  $280

 

Qty3: on request

 

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or by fax to: +31-50-3600390.

 

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Biological Activity:

 

NMDA antagonist; selectively blocks NMDA receptors containing the NR2B subunit; neuroprotective agent.

 

References: online 1

 

Kurihara, et al. Selective dysfunction of the vagal component of the baroflex following cerbral ischemia: protection by ifenprodil and flunarzine. Eur. J. Pharmacol. 1990, 190, 23.

 

Carter, et al. Ifenprodil and SL 82.0715 are antagonists at the polyamine site of the N-methyl-D-aspartate (NMDA) receptor. Eur. J. Pharmacol. 1989, 164, 611.

 

 

Chemical Name: 4-[(1R*,2S*)-2-(4-Benzyl-piperidin-1-yl)-1-hydroxy-propyl]-phenol (* relative stereochemistry)

 

Ifenprodil | NMDA antagonist | Axon Medchem | Axon 1156

 

Axon Ligands TM - Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.

axonmedchem.com © 2012

 

Axon Ligands in this field:

 

CP 101606 | NMDA antagonist

Ifenprodil | NMDA antagonist

Eliprodil | NMDA antagonist

N20C | NMDA antagonist

Gavestinel | Glycine antagonist

Ro 25-6981 | NMDA antagonist

Lamotrigine | Glutamate antago.

 

CFM-2 | AMPA antagonist

CNQX | AMPA/kanaite antagonist

DNQX | AMPA/kainate antagonist

GYKI 53655 | AMPA antagonist

YM-90K | AMPA antagonist

 

AZ 12216052 | mGluR8 PAM

BINA | mGluR2 PAM 

CPPHA | mGluR5 PAM

(S)-3,5-DHPG | mGluR1 agonist

VU-29 | mGuR5 PAM

LY 367385 | mGluR1a antagonist

YM 298198 | mGluR1 antagonist

Fenobam | mGluR5 antagonist

MPEP | mGluR5 antagonist