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Biological Activity:
Atypical antipsychotic lack of muscarinic activity
References: onlineref 1, 2
Y Liao et al. New sulfonyloxy piperazinyl-dibenzo-azapines as potential atypical antipsychotics: chemistry and pharmacological evaluation. J. Med. Chem. 1999, 42, 2235-2244.
Y Liao et al. Synthesis and pharmacological evaluation of triflate-substituted analogues of Clozapine: Identification of a novel atypical neuroleptic. J. Med. Chem. 1997, 40, 4146-4153.
D Jackson, H Wikström, Y Liao. Is clozapine an (partial) agonist at both dopamine D1 and D2 receptors? Psychopharmacology 1998, 138, 213-214.
Chemical Name: Trifluoro-methanesulfonic acid 11-(4-methyl-piperazin-1-yl)-dibenzo[b,f][1,4]oxazepin-2-yl ester
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