Isoclozapine | typical antipsychotic | Axon Ligands | Axon Medchem

	Chemistry Service Platform - CRO in Medicinal Chemistry × close
Axon Ligands (TM) - alphabetic: [A] [B] [C] [D] [E] [F] [G] [H] [I] [J] [K] [L] [M] [N] [O] [P] [Q] [R] [S] [T] [U] [V] [W] [X] [Y] [Z]

Isoclozapine

CAS 1977-08-8

C18H19ClN4 MW 326.83

Purity: >98%

Ordering Information:

Cat. No. Axon 1147

Qty1: 10 mg / 135 $178

Qty2: 50 mg / inquire

Qty3: on request

Send enquiry to: order@axonmedchem.com

or by fax to: +31-50-3600390.

Biological Activity:

typical antipsychotic; 2-Cl analogue of clozapine, atypical antipsychotic

* useful tool compound in comparison with clozapine; distinctly typical vs atypical profile

References: online 1, 2

Kapur et al. Increasing D2 affinity results in the loss of clozapine's atypical antipsychotic action. Neuroreport. 13(6):831-835, May 7, 2002.

Seeman P. Atypical Antipsychotics: Mechanisms of Action.Can J Psychiatry 2002;47:2738.

Chemical Name: 2-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine

Isoclozapine | typical antipsychotic | Axon Medchem | Axon 1147

Axon Ligands^TM

Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.