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Clozapine

CAS 5786-21-0

C18H19ClN4 MW 326.83

Purity: 99%

Ordering Information:

Cat. No. Axon 1146

Qty1: 10 mg / €45  $59

Qty2: 50 mg / €95  $124

Qty3: on request

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Biological Activity:   A putative atypical antipsychotic; Clozapine has been shown to be superior in efficacy in treating schizophrenia, however, the drug is not indicated for first-line use because of its association with agranulocytosis and seizures.   References: online 1, 2, 3   Kapur et al. Increasing D2 affinity results in the loss of clozapine's atypical antipsychotic action. Neuroreport. 13(6):831-835, May 7, 2002.   Seeman P. Atypical Antipsychotics: Mechanisms of Action.Can J Psychiatry 2002;47:27–38.     Chemical Name: 8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine

Clozapine | Atypical antipsychotic | Axon Medchem | Axon 1146

Axon LigandsTM Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.

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