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Biological Activity:
Partial dopamine D2 and 5-HT1A receptor agonist and 5-HT2A receptor antagonist; T1/2 about 46 hrs; oral active; atypical antipsychotic.
References: online ref 1
Aripiprazole - WHO Drug Information 11/1: 34, 1997.
DR Sibley et al. Pharmacological characterization of OPC-14597, a novel antipsychotic agent, using cloned dopamine and serotonin receptors. Neuropsychopharmacology 1994, 10, 252S.
Chemical Name: 7-{4-[4-(2,3-Dichloro-phenyl)-piperazin-1-yl]-butoxy}-3,4-dihydro-1H-quinolin-2-one
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