Sertindole | 5-HT2 and D2 antagonist | Axon Ligands | Axon Medchem

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Sertindole - Lu 23-174

CAS 106516-24-9

C₂₄H₂₆ClFN₄O MW 440.94

Purity: 99%

Ordering Information:

Cat. No. Axon 1141

Qty1: 10 mg (research sample) / 85 $111

Qty2: 50 mg (research sample) / 340 $442

Qty3: on request

Send enquiry to: order@axonmedchem.com

or by fax to: +31-50-3600390.

Biological Activity:

5-HT₂, D₂ and α₁ antagonist; Sertindole is an atypical antipsychotic with prominent selectivity for the brain limbic area and long lasting.

References:

Hale A, Azorin JM, Kasper S & al: Sertindole is associated with a low level of extrapyramidal symptoms in schizophrenic patients: Results of a phase III trial. Int J Psychiatry Clin Pract 4/1: 47-54, 2000 - Hale A, Azorin JM, Kasper S & al: Sertindole improves both the positive and negative symptoms of schizophrenia: Results of a phase III trial. Int J Psychiatry Clin Pract 4/1: 55-62, 2000.

S Miyamoto et al. Treatments for schizophrenia: a critical review of pharmacology and mechanisms of action of antipsychotic drugs. Mol. Psychiatry 2005, 10, 79-104.

Chemical Name: 1-[2-[4-[5-Chloro-1-(4-fluorophenyl)-1h-indol-3-yl]-1-piperidinyl]ethyl]-2-imidazolidinone

Sertindole | 5-HT2 and D2 antagonist | Axon Ligands | Axon Medchem | Axon 1141 | Lu 23-174

Axon Ligands^TM

Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.