Sertindole - LU 23-174

Based on 12 reference(s) in Google Scholar 9 10 12

Axon 1141

CAS [106516-24-9]

MF C24H26ClFN4O
MW 440.94

Purity: 99%
Soluble in DMSO

Sertindole

Description

5-HT2, D2 and α1 antagonist; Sertindole is an atypical antipsychotic with prominent selectivity for the brain limbic area and long lasting

A Hale, JM Azorin, S Kasper et al. Sertindole is associated with a low level of extrapyramidal symptoms in schizophrenic patients: Results of a phase III trial. Int. J. Psychiatry Clin. Pract. 2000, 4, 47-54.

S Miyamoto et al. Treatments for schizophrenia: a critical review of pharmacology and mechanisms of action of antipsychotic drugs. Mol. Psychiatry2005, 10, 79-104.

CNS D2 5-HT2 A17

5-HT2, D2 and α1 adrenoceptor antagonist

Chemical name

1-(2-{4-[5-Chloro-1-(4-fluoro-phenyl)-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-imidazolidin-2-one

Parent CAS No.

[106516-24-9]

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Sertindole - LU 23-174

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Sertindole - LU 23-174

Description

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