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Axon Ligands (TM) - alphabetic: [A] [B] [C] [D] [E] [F] [G] [H] [I] [J] [K] [L] [M] [N] [O] [P] [Q] [R] [S] [T] [U] [V] [W] [X] [Y] [Z]

 

 

 

  

LY 393558

CAS 271780-64-4

C26H31FN4O4S2  MW 546.67

Purity: 99%

 

 

 

 

Ordering Information:

 

Cat. No. Axon 1139     Prime Source

 

Qty1: 10 mg / €135  $176

Promotion: 2 x 10 mg @ €180  $234

Qty2: 50 mg / €505  $657

Promotion: 2 x 50 mg @ €740  $962

Qty3: on request

 

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Biological Activity:

 

Serotonin reuptake inhibitor and 5-HT1B/1D antagonist

 

References: online ref 1

 

SN Mitchell et al. LY393558, a 5-hydroxytryptamine reuptake inhibitor and 5-HT"1"B"/"1"D receptor antagonist: effects on extracellular levels of 5-hydroxytryptamine in the guinea pig and rat. Eur. J. Pharmacol. 2001, 432(1), 19-27.

 

 

Chemical Name: 1-{2-[4-(6-Fluoro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]-ethyl}-3-isopropyl-6-methanesulfonyl-3,4-dihydro-1H-benzo[1,2,6]thiadiazine 2,
2-dioxide

 

LY-393558 | 5-HT reuptake inhibitor, 5-HT1B/1D antagonist | Axon Medchem | Axon 1139 | LY393558

 

Axon Ligands TM - Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.

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Axon Ligands In The Field: e.g.

 

GR127935 | 5-HT1B/1D antagonist

GMC2-29 | 5-HT1B/1D antagonist

GMC3-15 | 5-HT1B/1D antagonist

GMC15-27 | 5-HT1B/1D antagonist

GMC2-113 | 5-HT1B antagonist

GMC2-118 | 5-HT1B/1D antagonist

SB 216641 | 5-HT1B antagonist

 

LY-393558 | 5-HT reuptake inhibitor, 5-HT1B/1D antagonist

CGS 12066B | 5-HT1B agonist

 

Citalopram | SSRI

Fluoxetine | SSRI

Fluvoxamine | SSRI

Paroxetine | SSRI

Sertraline | SSRI