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Biological Activity:
Potent and selective PDE4 inhibitor
References: online ref 1, ref 2
Huang Z et al. L-454,560, a potent and selective PDE4 inhibitor with in vivo efficacy in animal models of asthma and cognition. Biochemical Pharmacology 2007, 73(12), 1971-1981.
Chemical Name: 6-[1-Methyl-1-(methylsulfonyl)ethyl]-8-[3-[(E)-2-(3-methyl-1,2,4-oxadiazol-5-yl)-2-[4-(methylsulfonyl)phenyl]vinyl]phenyl]quinoline
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