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L-454,560

CAS 346629-30-9

C31H29N3O5S2  MW 587.71

Purity: >98 %

 

 

 

 

 

Ordering Information:

 

Cat. No. Axon 1127

 

Qty1: 5 mg (research sample) / €165  $215

 

Qty2: 25 mg (research sample) / inquire

 

Qty3: on request Contract research synthesis

 

Send enquiry to: order@axonmedchem.com

or by fax to: +31-50-3600390.

 

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Biological Activity:

 

Potent and selective PDE4 inhibitor

 

References: online ref 1, ref 2

 

Huang Z et al. L-454,560, a potent and selective PDE4 inhibitor with in vivo efficacy in animal models of asthma and cognition. Biochemical Pharmacology 2007, 73(12), 1971-1981. 

 

 

 

Chemical Name: 6-[1-Methyl-1-(methylsulfonyl)ethyl]-8-[3-[(E)-2-(3-methyl-1,2,4-oxadiazol-5-yl)-2-[4-(methylsulfonyl)phenyl]vinyl]phenyl]quinoline

 

L-454,560 | PDE4 inhibitor | Axon Medchem | Axon 1127 | L-454560 | L454560

 

Axon Ligands TM - Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.

axonmedchem.com © 2012

 

Axon Ligands In The Field:

 

BAY 19-8004 | PDE4 inhibitor

Cilomilast | PDE4 inhibitor

L 454560 | PDE4 inhibitor

Rolipram | PDE4 inhibitor

R-(-)-Rolipram | PDE4 inhibitor

 

Olprinone | PDE3 inhibitor

Parogrelil | PDE3 inhibitor

Zardaverine | PDE3/4 inhibitor

 

PDE5 inhibitor | Axon 1709