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BACE-1 inhibitor

 

 

CAS 797035-11-1

C31H38N4O5S  MW 578.73

Purity: 99% (optically pure)

 

 

 

 

Ordering Information:

 

Cat. No. Axon 1125    2012 Promotion

 

Qty1: 2 mg (research sample) / €145  $189

Promotion: 2 x 2 mg @ €220  $286

Qty2: 5 mg (research sample) / €245  $319

Promotion: 2 x 5 mg @ €380  $494

Qty3: on request

 

Send enquiry to: order@axonmedchem.com

or by fax to: +31-50-3600390.

 

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Biological Activity:

 

Potent and selective cell-permeable inhibitor of human β-secretase (BACE-1)

 

References: onlineref 1

 

Huntington Potter and David Dressler. The potential of BACE inhibitors for Alzheimer's therapy. Nature Biotech. 2000, 18, 125 - 126.

 

SJ Stachel et al. Structure-based design of potent and selective cell-permeable inhibitors of human β-secretase (BACE-1). J. Med. Chem. 2004, 47, 6447-6450. 

 

 

 

Chemical Name: N-[(1S,2R)-3-(cyclopropylamino)-2-hydroxy-1-(phenylmethyl)propyl]-5-[methyl(methylsulfonyl)amino]-N'-[(1R)-1-phenylethyl]-1,3-Benzenedicarboxamide

 

BACE-1 inhibitor | Axon Medchem | Axon 1125

 

Axon Ligands TM - Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.

axonmedchem.com © 2012

 

Axon Ligands In The Field:

 

BACE-1 inhibitor | β-Secretase inh.

BZ | γ-Secretase inhibitor

DAPT | γ-Secretase inhibitor

DBZ | γ-Secretase inhibitor

 

 

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