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Biological Activity:
Potent and selective cell-permeable inhibitor of human β-secretase (BACE-1)
References: onlineref 1
Huntington Potter and David Dressler. The potential of BACE inhibitors for Alzheimer's therapy. Nature Biotech. 2000, 18, 125 - 126.
SJ Stachel et al. Structure-based design of potent and selective cell-permeable inhibitors of human β-secretase (BACE-1). J. Med. Chem. 2004, 47, 6447-6450.
Chemical Name: N-[(1S,2R)-3-(cyclopropylamino)-2-hydroxy-1-(phenylmethyl)propyl]-5-[methyl(methylsulfonyl)amino]-N'-[(1R)-1-phenylethyl]-1,3-Benzenedicarboxamide
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