|
Biological Activity:
a norepinephrine-dopamine reuptake inhibitor (NDRI); a potent metabolite of bupropion; radafaxine is a (+)-isomer of hydroxybupropion.
References: online 1, 2
ND Volkow et al. The slow and long-lasting blockade of dopamine transporters in human brain induced by the new antidepressant drug radafaxine predict poor reinforcing effects. Biol Psychiatry. 2005, 57(6), 640-6.
Chemical Name: (2S,3S)-2-(3-Chloro-phenyl)-3,5,5-trimethyl-morpholin-2-ol hydrochloride
|