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Axon Ligands (TM) - alphabetic: [A] [B] [C] [D] [E] [F] [G] [H] [I] [J] [K] [L] [M] [N] [O] [P] [Q] [R] [S] [T] [U] [V] [W] [X] [Y] [Z]

 

 

 

  

Radafaxine hydrochloride

BW 306U; GW 353162A

CAS 106083-71-0

192374-14-4 (free base)

C13H18ClNO2.HCl  MW 275.34

Purity: >98% (optically pure)

 

 

 

 

Ordering Information:

 

Cat. No. Axon 1123    Prime Source Promotion

 

Qty1: 5 mg (research sample) / €115  $150

 

Qty2: 25 mg (research sample) / €460  $598

 

Qty3: on request contract research synthesis

 

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Biological Activity:

 

a norepinephrine-dopamine reuptake inhibitor (NDRI); a potent metabolite of bupropion; radafaxine is a (+)-isomer of hydroxybupropion.

 

References: online 1, 2

 

ND Volkow et al. The slow and long-lasting blockade of dopamine transporters in human brain induced by the new antidepressant drug radafaxine predict poor reinforcing effects. Biol Psychiatry. 2005, 57(6), 640-6.

 

 

Chemical Name: (2S,3S)-2-(3-Chloro-phenyl)-3,5,5-trimethyl-morpholin-2-ol hydrochloride

 

Radafaxine | NDRI | Axon Medchem | Axon 1123 | BW306U - GW353162A - Hydroxybupropion (+)

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Axon Ligands in The Filed:

 

Bupropion | NDRI

Radafaxine | NDRI

 

 

Term NDRI

Norepinephrine-dopamine reuptake inhibitor (NDRI).