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Biological Activity:
Selective MEK1 and MEK2 inhibitor; brain penetrant in vivo
References:
Wang et al. Significant neuroprotection against ischemic brain injury of inhibition of MEK1 protein kinase in mice: exploration of potential mechanism associated with apoptosis. J. Pharmacol. Exp. Ther. 2003, 304, 172-178.
Chemical Name: α-[Amino[(4-aminophenyl)thio]methylene]-2-(trifluoromethyl)benzeneacetonitrile
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