Chemistry Service Platform - CRO in Medicinal Chemistry

Axon Ligands (TM) - alphabetic: [A] [B] [C] [D] [E] [F] [G] [H] [I] [J] [K] [L] [M] [N] [O] [P] [Q] [R] [S] [T] [U] [V] [W] [X] [Y] [Z]

 

 

 

  

SL-327

 

 

CAS 305350-87-2

C16H12F3O3S   MW 335.35 

Purity: 99%

Soluble in DMSO

 

 

 

 

Ordering Information:

 

Cat. No. Axon 1122

 

Qty1: 10 mg / €105  $137

Promotion: 2 x 10 mg @ €160  $208

Qty2: 50 mg / €405  $527

Promotion: 2 x 50 mg @ €580  $754

Qty3: on request

 

Send enquiry to: order@axonmedchem.com

or by fax to: +31-50-3600390.

 

Contact us for payment and tech support.

Biological Activity:

 

Selective MEK1 and MEK2 inhibitor; brain penetrant in vivo

 

References:

 

Wang et al. Significant neuroprotection against ischemic brain injury of inhibition of MEK1 protein kinase in mice: exploration of potential mechanism associated with apoptosis. J. Pharmacol. Exp. Ther. 2003, 304, 172-178.

 

 

 

Chemical Name: α-[Amino[(4-aminophenyl)thio]methylene]-2-(trifluoromethyl)benzeneacetonitrile

 

SL 327 | MEK inhibitor | Axon Medchem | Axon 1122 | SL327

Axon Ligands TM - Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.

axonmedchem.com © 2012

 

Axon Ligands In This Field:

 

AZD 6244 | MEK inhibitor

GSK 1120212 | MEK inhibitor

PD 98059 | MEK inhibitor

PD 184352 | MEK inhibitor

PD 0325901 | MEK inhibitor

SL 327 | MEK inhibitor

 

BIRB 796 | p38 MAPK inhibitor

PD 169316 | p38 MAPK inhibitor

SB 203580 | p38 MAPK inhibitor

SB 202190 | p38 MAPK inhibitor

SCIO 469 | p38 MAPK inhibitor

SD 169 | p38α MAPK inhibitor

 

BIX 02189 | MEK5/ERK5 inhibitor

FR 180204 | ERK inhibitor

XMD8-92 | BMK1 inhibitor

 

Click Here To See Featured Cell Signaling and Oncology Ligands from Axon Ligands Collection