Axon Ligands (TM) - alphabetic: [A] [B] [C] [D] [E] [F] [G] [H] [I] [J] [K] [L] [M] [N] [O] [P] [Q] [R] [S] [T] [U] [V] [W] [X] [Y] [Z]

NBI 34060 - Indiplon

CAS 325715-02-4

C20H16N4O2S  MW 376.43

Purity: 99 %

Soluble in DMSO

Ordering Information:

Cat. No. Axon 1121      

Qty1: 10 mg / €105  $137

Qty2: 50 mg / €375  $488

Qty3: on request

Send enquiry to: order@axonmedchem.com

or by fax to: +31-50-3600390.

Contact us for payment and tech support.

Biological Activity:   A high-affinity positive allosteric modulator with selectivity for alpha1 subunit-containing GABAA receptors; NBI 34060 modulates specific GABAA receptor subtypes at the benzodiazepine site; nonbenzodiazepine hypnotic.   References: online 1   RE Petroski et al. Indiplon is a high-affinity positive allosteric modulator with selectivity for alpha1 subunit-containing GABAA receptors. J. Pharmacol. Exp. Ther. 2006, 317(1), 369-77. [abstract]   SK Sullivan et al. Characterization of the Interaction of Indiplon, a Novel Pyrazolopyrimidine Sedative/Hypnotic, with the GABAA Receptor. J. Pharmacol. Exp. Ther. 2004, 311(2), 537-546. [abstract]     Chemical Name: N-Methyl-N-{3-[3-(thiophene-2-carbonyl)-3H-pyrazolo[1,5-a]pyrimidin-7-yl]-phenyl}-acetamide

NBI 34060 | GABAA PAM | Axon Medchem | Axon 1121 | NBI34060 - Indiplon

Axon Ligands TM - Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research and synthesis.

axonmedchem.com © 2012

Axon Ligands in the area:

CP 615003 | GABAA agonist

L-838417 | GABAA agonist

Pagoclone | GABAA α2/3 agonist

SL 651498 | GABAA agonist

TP-003 | GABAA α3 agonist

GS 39783 | GABAB PAM