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GR 159897

CAS 158848-32-9

C23H27FN2O2S  MW 414.54

Purity: 99%, >98%ee

Soluble in DMSO to 48 mM

Ordering Information:

Cat. No. Axon 1119

Qty1: 5 mg / €115  $150

Qty2: 25 mg / inquire

Qty3: on request

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Biological Activity:   Highly potent, oral and selective non-peptide neurokinin NK2 receptor antagonist   References:   DM Walsh et al. The anxiolytic-like activity of GR 159897, a non-peptide NK2 receptor antagonist, in rodent and primate models of anxiety. Psychopharmacology 1995, 121, 186-191. [online]   AWJ Cooper et al. GR 159897 and related analogues as highly potent, orally active non-peptide neurokinin NK2 receptor antagonists. Bioorg. Med. Chem. Lett. 1994, 4(16), 1951. [online]       Chemical Name: 3-[2-(4-(R)-Benzenesulfinylmethyl-4-methoxy-piperidin-1-yl)-ethyl]-5-fluoro-1H-indole

GR 159897 | NK2 antagonist | Axon Medchem | Axon 1119 | GR159897

Axon Ligands TM - Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.

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