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SSR 149415 - Nelivaptan

CAS 439687-69-1

C₃₀H₃₂ClN₃O₈S   MW 630.11

Purity: 98% (optically pure)

Ordering Information:

Cat. No. Axon 1114          Prime Source

Qty1: 5 mg (research sample) / €135  $176

Promotion: 2 x 5 mg  @  €200  $260

Qty2: 25 mg (research sample) / €535  $696

Promotion: 2 x 25 mg  @  €780  $1014

Qty3: on request

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Biological Activity:   Selective and orally active non-peptide antagonist of vasopressin V(1b) receptor, potential drug for treatment of anxiety and depression.   References: online ref 1   Griebel G et al. Anxiolytic- and antidepressant-like effects of the non-peptide vasopressin V1b receptor antagonist, SSR149415, suggest an innovative approach for the treatment of stress-related disorders. Proc. Natl. Acad. Sci. U.S.A. 2002, 99(9), 6370–5.   Serradeil-Le Gal C et al. An overview of SSR149415, a selective nonpeptide vasopressin V(1b) receptor antagonist for the treatment of stress-related disorders. CNS drug reviews 2005, 11(1), 53–68.     Chemical Name:(2S,4R)-1-(5-chloro-1-((2,4-dimethoxyphenyl)sulfonyl)-3-(2-methoxyphenyl)-2-oxo-2,3-dihydro-1H-indol-3-yl)-4-hydroxy-N,N-dimethyl-2-pyrrolidinecarboxamide

SSR 149415 | Vasopressin V1B antagonist | Axon Medchem | Axon 1114 | SSR149415 | SSR-149,415 - Nelivaptan

Axon Ligands TM - Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.

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