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AM-36 dihydrochloride

CAS 199467-52-2 (free base)

C27H39ClN2O2.2HCl  MW 531.99

Purity: 99%

Soluble in DMSO

Ordering Information:

Cat. No. Axon 1113    Exclusive Promotion

Qty1: 10 mg / €145  $189 

Qty2: 50 mg / €545  $709 

Qty3: on request

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Biological Activity:   Na+ channel blocker; neuroprotective agent   References: online ref 1, 2   J. K. Callaway et al. Delayed Treatment With AM-36, a Novel Neuroprotective Agent, Reduces Neuronal Damage After Endothelin-1–Induced Middle Cerebral Artery Occlusion in Conscious Rats. Stroke. 1999, 30, 2704-2712.   J. K Callaway et al. Incorporation of sodium channel blocking and free radical scavenging activities into a single drug, AM-36, results in profound inhibition of neuronal apoptosis. Br. J. Pharmacol. 2001, 132, 1691–1698.       Chemical Name: 1-(2-(4-chlorophenyl)-2-hydroxy)ethyl-4-(3,5-bis(1,1-dimethyl)-4-hydroxyphenyl)methylpiperazine dihydrochloride

AM-36 | Na+ Channel Blocker | Axon Medchem | Axon 1113 | AM36

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