BMS 204352 - Flindokalner | K Channel Opener | Axon Medchem

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BMS 204352 - Flindokalner

S-(+)-BMS-204352

CAS 187523-35-9

C16H10ClF4NO2 MW 359.71

Purity: 99%, >99%ee

Ordering Information:

Cat. No. Axon 1112 Exclusive Promotion

Qty1: 5 mg (research sample) / €165 $215

Qty2: 25 mg (research sample) / €620 $806

Qty3: on request

Send enquiry to: order@axonmedchem.com

or by fax to: +31-50-3600390.

Biological Activity:

Maxi-K channel opener, potential therapeutic for the treatment of stroke; more active S-(+)-enantiomer in comparison with R-(-)-enantiomer (Axon 1309).

References: online ref 1, 2

R Krishna et al. Pharmacokinetics and dose proportionality of BMS-204352 after intraarterial administration to rats. Biopharm. Drug Dispos. 2002, 23(6), 233-7.

MPG Korsgaard et al. Anxiolytic Effects of Maxipost (BMS-204352) and Retigabine via Activation of Neuronal K_v7 Channels. J. Pharmacol. Exp. Ther. 2005, 314, 282-292.

Chemical Name: (S)-(+)-(5-Chloro-2-methoxyphenyl)-3-fluro-6-(trifluoromethyl)-2,3-dihydro-1H-indol-2-one

BMS 204352 | K channel opener | Axon Medchem | Axon 1112 | S-(+)-BMS204352 - Flindokalner - MaxiPost

Axon Ligands ^TM - Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.