MDL-100009

(S)-(-)-MDL-100,907

CAS 175673-57-1

C22H28FNO3  MW 373.465

Purity: 99%, >99%ee

Ordering Information:

Cat. No. Axon 1105

Qty1: 5 mg (research sample) / €135  $176

Qty2: 25 mg (research sample) / inquire

Qty3: on request contract research synthesis

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Biological Activity:   S-enantiomer of MDL 100151 (Axon 1103); opposite enantiomer of MDL 100907 (Axon 1104), selective 5-HT2A antagonist.   References: online 1, 2   T Ullrich and KC Rice. A practical synthesis of the serotonin 5-HT2a receptor antagonist mdl 100907, its enantiomer and their 3-phenolic derivatives as precursors for [11c]labeled pet ligands. Bioorg. Med. Chem. 2000, 8(10), 2427-2432.   J H Kehne et al. Effects of the Selective 5-HT2A Receptor Antagonist MDL 100,907 on MDMA-Induced Locomotor Stimulation in Rats. Neuropsychopharmacology 1996, 15, 116-124.     Chemical Name: (S)-(-)-α-(2,3-Dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol ; also as M 100009

MDL-100009 | 5-HT2A antagonist | Axon Medchem | Axon 1105 | (S)-(-) MDL 100907

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Axon Ligands In The Field:

MDL-100907 | 5-HT2A antagonist

MDL-100009 | 5-HT2A antagonist

MDL-100151 | 5-HT2A antagonist

MDL 105725 | 5-HT2A antagonist

Eplivanserin | 5-HT2A inverse agonist

Sertindole | 5-HT2/D2 antagonist

Axon Ligands ^TM

Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.

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