MDL-100151 | 5-HT2A antagonist | Axon Ligands | Axon Medchem

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MDL 100151

(+/-)-MDL-100,907

CAS 139290-69-0

C22H28FNO3 MW 373.465

Purity: >98%

Ordering Information:

Cat. No. Axon 1103

Qty1: 10 mg / 135 $176

Qty2: 50 mg / inquire

Qty3: on request

Send enquiry to: order@axonmedchem.com

or by fax to: +31-50-3600390.

Biological Activity:

Selective 5-HT2A antagonist; rac-M 100907, its more active enantiomer is (+)-MDL 100907 (Axon 1104); Reference standard for [11C]MDL100907 in PET/SPECT study.

References: online 1, 2, 3

HO Kalkman et al. Cataleptogenic effect of subtype selective 5-HT receptor antagonists in the rat. Eur. J. Pharmacol. 1998, 343(2-3), 201-7.

JH Kehne et al. Effects of the Selective 5-HT_2A Receptor Antagonist MDL 100,907 on MDMA-Induced Locomotor Stimulation in Rats. Neuropsychopharmacology 1996, 15, 116-124.

C Sanchez et al. In-vivo assessment of 5-HT2A and 5-HT2C antagonistic properties of newer antipsychotics. Behav. Pharmacol. 2000, 11, 291-98.

Chemical Name: (2,3-Dimethoxy-phenyl)-{1-[2-(4-fluoro-phenyl)-ethyl]-piperidin-4-yl}-methanol; MDL 100,151

MDL-100151 | 5-HT2A antagonist | Axon Medchem | Axon 1103 | (+/-)-MDL 100907

axonmedchem.com Š 2012

Axon Ligands In The Field:

MDL-100907 | 5-HT2A antagonist

MDL-100009 | 5-HT2A antagonist

MDL-100151 | 5-HT2A antagonist

MDL 105725 | 5-HT2A antagonist

Eplivanserin | 5-HT2A antagonist

Ketanserin | 5-HT2A antagonist

Risperidon | 5-HT2A antagonist

Sertindole | 5-HT2/D2 antag.

Ziprasidone | 5-HT2/D2 antag.