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Axon Ligands (TM) - alphabetic: [A] [B] [C] [D] [E] [F] [G] [H] [I] [J] [K] [L] [M] [N] [O] [P] [Q] [R] [S] [T] [U] [V] [W] [X] [Y] [Z]

 

 

  

LY 426965

 

 

CAS 228418-82-4

C28H38N2O2 MW 420.6

Purity: >98%

 

 

 

 

Ordering Information:

 

Cat. No. Axon 1094

 

Qty1: 10 mg (research sample) / inquire

 

Qty2: 50 mg (research sample) / inquire

 

Qty3: on request contract research synthesis

 

Send enquiry to: order@axonmedchem.com

or by fax to: +31-50-3600390.

 

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Biological Activity:

 

Potent full oral 5-HT1A antagonist, more active S-(+)-enantiomer of (±)LY 426965 (Axon 1093).

 

References: online 1, 2

 

Rasmussen et al. The Novel 5-Hydroxytryptamine1A Antagonist LY426965: Effects on Nicotine Withdrawal and Interactions with Fluoxetine. JPET 2000, 294(2), 688-700.

 

 

 

 

Chemical Name: (S)-(+)-1-Cyclohexyl-4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-2-phenyl-butan-1-one

 

LY 426965 | 5-HT1a antagonist | Axon Medchem | Axon 1094 | LY426965 (S)-(+)

 

Axon Ligands TM - Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.

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Axon 5-HT1A Ligands: e.g.

8-OH-DPAT | 5-HT1A agonist

(+)-8-OH-DPAT | 5-HT1A agonist

(-)-NPPCC | 5-HT1A agonist

S 14506 | 5-HT1A agonist

Desmethyl S14506

U 92016A | 5-HT1A agonist

LY 426965 | 5-HT1A antagonist

p-MPPF | 5-HT1A antagonist

p-MPPI | 5-HT1A antagonist

WAY 100135 | 5-HT1A antagonist

(S)-WAY100135 | 5-HT1A antag.

WAY 100635 | 5-HT1A antagonist

DWAY | 5-HT1A antagonist

FWAY | 5-HT1A antagonist

 

Axon 5-HT1B/1D Ligands: e.g.

CGS 12066B | 5-HT1B agonist 

Sumatriptan | 5-HT1B/1D agonist

GR 127935 | 5-HT1B/1D antagonist

GMC 2-29 | 5-HT1B/1D antagonist

GMC 3-15 | 5-HT1B/1D antagonist

GMC 15-27 | 5-HT1B/1D antag.

SB 216641 | 5-HT1B antagonist

LY 393558 | SRI, 5-HT1B/1D antag

 

Axon 5-HT1F Ligands:

LY 334370 | 5-HT1F agonist