p-MPPI | 5-HT1A antagonist | Axon Ligands | Axon Medchem

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p-MPPI

CAS 155204-23-2

220643-77-6 (HCl)

C25H27IN4O2 MW 542.42

Purity: >98%

Ordering Information:

Cat. No. Axon 1091

Qty1: 10 mg / 125 $163

Qty2: 50 mg / 425 $553

Qty3: on request

Send enquiry to: order@axonmedchem.com

or by fax to: +31-50-3600390.

Biological Activity:

Selective 5-HT1A antagonist; unlabelled standard in radiochemistry.

References: online ref 1

Thielen, et al. 4-(2′-Methoxyphenyl)-1-[2′-[N-(2′′-pyridinyl)-p-iodo-benzamido]ethyl]piperazine and 4-(2′-methoxyphenyl)-1-[2′-[N-(2′′-pyridinyl)-p-fluorobenzamido]ethyl]piperazine two new antagonists at pre- and postsynaptic serotonin-1A receptors. J. Pharmacol. Exp. Ther. 1996, 277, 661.

Kung, et al. 4-(Methoxyphenyl)-1-[2′-(n-2″-pyridinyl)-p-iodobenzamido]-ethyl-piperazine ([¹²⁵I]p-MPPI) as a new selective radioligand of serotonin-1A sites in rat brain: In vitro binding and autoradiographic studies. J. Pharmacol. Exp. Ther. 1995, 277, 429.

Chemical Name: 4-Iodo-N-{2-[4-(2-methoxy-phenyl)-piperazin-1-yl]-ethyl}-N-pyridin-2-yl-benzamide

p-MPPI | 5-HT1A antagonist | Axon Medchem | Axon 1091 | MPPI