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Axon Ligands (TM) - alphabetic: [A] [B] [C] [D] [E] [F] [G] [H] [I] [J] [K] [L] [M] [N] [O] [P] [Q] [R] [S] [T] [U] [V] [W] [X] [Y] [Z]

 

 

 

  

Desmethyl-S14506

 

 

CAS 135722-26-8

C23H24FN3O2 MW 434.51

Purity: 98%

 

 

 

 

Ordering Information:

 

Cat. No. Axon 1089

 

Qty1: 10 mg / inquire

 

Qty2: 50 mg / inquire

 

Qty3: on request

 

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or by fax to: +31-50-3600390.

 

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Biological Activity:

 

Precursor for labeling the 5-HT1A agonist, S14506, for PET study

 

References: online 1

 

LU et al. Alternative methods for labeling the 5-HT[1A] receptor agonist, 1-[2-(4-fluorobenzoylamino)ethyl]-4-(7-methoxynaphthyl)piperazine (S14506), with carbon-11 or fluorine-18. J. Labelled Compd. Radiopharm. 2005, 48(13), 971-981.

 

 

 

 

 

 

 

 

Chemical Name: 4-Fluoro-N-{2-[4-(7-hydroxy-naphthalen-1-yl)-piperazin-1-yl]-ethyl}-benzamide

 

Desmethyl S14506 | 5-HT1A agonist | Axon Medchem | Axon 1089 - Desmethyl S 14506

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Axon 5-HT1A Ligands: e.g.

8-OH-DPAT | 5-HT1A agonist

(+)-8-OH-DPAT | 5-HT1A agonist

(-)-NPPCC | 5-HT1A agonist

S 14506 | 5-HT1A agonist

Desmethyl S14506

U 92016A | 5-HT1A agonist

LY 426965 | 5-HT1A antagonist

p-MPPF | 5-HT1A antagonist

p-MPPI | 5-HT1A antagonist

WAY 100135 | 5-HT1A antagonist

WAY 100635 | 5-HT1A antagonist

DWAY | 5-HT1A antagonist

FWAY | 5-HT1A antagonist

 

Axon 5-HT1B/1D Ligands: e.g.

CGS 12066B | 5-HT1B agonist 

Sumatriptan | 5-HT1B/1D agonist

GR 127935 | 5-HT1B/1D antagonist

GMC 2-29 | 5-HT1B/1D antagonist

GMC 3-15 | 5-HT1B/1D antagonist

GMC 15-27 | 5-HT1B/1D antag.

SB 216641 | 5-HT1B antagonist

LY 393558 | SRI, 5-HT1B/1D antag

 

Axon 5-HT1F Ligands:

LY 334370 | 5-HT1F agonist