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Biological Activity:
PD 128907 is a selective D3 dopamine receptor agonist; (-)-enantiomer is less active in comparison with (+)-enantiomer (Axon 1073).
References: online ref 1, 2
Pugsley et al. Neurochemical and functional characterization of the preferentially selective dopamine D3 agonist PD 128907. J. Pharmacol. Exp. Ther. 1995, 275 1355.
Witkin et al. Atypical antipsychotic-like effects of the dopamine D3 receptor agonist (+)-PD 128907. Eur. J. Pharmacol. 1998, 347, R1.
Chemical Name: (-)-(4aS,10bS)-3,4,4a,10b-Tetrahydro-4-propyl-2H,5H-[1]benzopyrano[4,3-b]-1,4-oxazin-9-ol hydrochloride; also as trans-(-)-PD128907 hydrochloride
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