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Axon Ligands (TM) - alphabetic: [A] [B] [C] [D] [E] [F] [G] [H] [I] [J] [K] [L] [M] [N] [O] [P] [Q] [R] [S] [T] [U] [V] [W] [X] [Y] [Z]

 

 

 

  

(+)-PD 128907 hydrochloride

 

 

CAS300576-59-4

C14H19NO3·HCl 

MW 285.77

Purity: >99%, >99% ee

 

 

 

 

Ordering Information:

 

Cat. No. Axon 1073      Prime Source

 

Qty1: 5 mg / €135  $176

Promotion: 2 x 5 mg  @  €200  $260

Qty2: 25 mg €475  $618

Promotion: 2 x 25 mg  @  €700  $910

Qty3: on request

 

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Biological Activity:

 

Standard selective D3 dopamine receptor agonist, more active enantiomer of trans-(+/-)-PD 128907 (Axon 1072).

 

References: online ref 1, 2

 

Pugsley et al. Neurochemical and functional characterization of the preferentially selective dopamine D3 agonist PD 128907. J. Pharmacol. Exp. Ther. 1995, 275 1355.

 

Witkin et al. Atypical antipsychotic-like effects of the dopamine D3 receptor agonist (+)-PD 128907. Eur. J. Pharmacol. 1998, 347, R1.

 

 

 

Chemical Name: (+)-(4aR,10bR)-3,4,4a,10b-Tetrahydro-4-propyl-2H,5H-[1]benzopyrano[4,3-b]-1,4-oxazin-9-ol hydrochloride

 

(+)-PD 128907 | D3 agonist | Axon Medchem | Axon 1073 | (+)-PD128907, (+)-PD 128,907 

 

Axon Ligands TM - Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.

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Axon DRD3 related ligands: e.g.

7-hydroxy-DPAT | D3 agonist

(R)-(+)-7-OH-DPAT | D3 agonist

(±)-PD 128907 | D3 agonist

(+)-PD 128907 | D3 agonist

ST 198 | D3 antagonist

U 99194 | D3 antagonist

GR 103691 | D3 antagonist

 

Other Dopamine Ligands: e.g.

ABT 724 | D4 agonist

CP 226269 | D4 agonist

S-(+)-Dinapsoline | D1 agonist

5-hydroxy-DPAT | D2 agonist

(S) 5-hydroxy-DPAT | D2 agonist

Molindone | D2 antagonist

N-0426 | DA agonist

N 0734 | DA agonist  

NNC 776 | D1 antagonist

R(-)-NPA | D2 agonist

Rotigotine - N-0437 | DA agonist

(-)-Rotigotine | DA agonist

RU 24213 | D2 agonist

(+)-PHNO | D2 agonist

Piribedil | Dopamine agonist

PPHT - N-0434 | D2 agonist

SKF-83566 | D1 antagonist

ST 148 | D2 antagonist

TL 99 | Dopamine agonist

TL 102 | Dopamine agonist

TL 232 | Dopamine agonist