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Biological Activity:
Potent and selective dopamine receptor agonist as anti-Parkinson drug; its S-(-)-enantiomer (Axon 1040) is more active vs (R)-(+)-enantiomer (Axon 1039).
* N-0437, N-0434 ((±)-PPHT, Axon 1035) and N-0734 (Axon 1041) are potent and selective DA agonists that lack significant alpha 2 activity.
References: onlineref 1, 2, 3, 4
Van der Weide, J. et al. Pharmacological profiles of three new, potent and selective dopamine receptor agonists: N-0434, N-0437 and N-0734. Eur. J. Pharmacol. 1986,125, 273-282.
Chemical Name: 6-(propyl-(2-thiophen-2-ylethyl)amino)tetralin-1-ol
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