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Axon Ligands (TM) - alphabetic: [A] [B] [C] [D] [E] [F] [G] [H] [I] [J] [K] [L] [M] [N] [O] [P] [Q] [R] [S] [T] [U] [V] [W] [X] [Y] [Z]

 

 

 

  

N-0437

 

 

CAS 92206-54-7 (free base)

102120-99-0 (HCl)

C19H25NOS  MW 315.47

Purity: >98%

 

 

 

 

Ordering Information:

 

Cat. No. Axon 1038

 

Qty1: 10 mg (research sample) /€135  $176

 

Qty2: 50 mg (research sample) / €535  $696

 

Qty3: on request, contract research synthesis

 

Send enquiry to: order@axonmedchem.com

or by fax to: +31-50-3600390.

 

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Biological Activity:

 

Potent and selective dopamine receptor agonist as anti-Parkinson drug; its S-(-)-enantiomer (Axon 1040) is more active vs (R)-(+)-enantiomer (Axon 1039).

 

* N-0437, N-0434 ((±)-PPHT, Axon 1035) and N-0734 (Axon 1041) are potent and selective DA agonists that lack significant alpha 2 activity.

 

References: onlineref 1, 2, 3, 4

 

Van der Weide, J. et al. Pharmacological profiles of three new, potent and selective dopamine receptor agonists: N-0434, N-0437 and N-0734. Eur. J. Pharmacol. 1986,125, 273-282.

 

 

 

Chemical Name: 6-(propyl-(2-thiophen-2-ylethyl)amino)tetralin-1-ol

 

N-0437 | DA agonist | Axon Medchem | Axon 1038 | N0437

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Axon Ligands TM

 

Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.