Chemistry Service Platform - CRO in Medicinal Chemistry

Axon Ligands (TM) - alphabetic: [A] [B] [C] [D] [E] [F] [G] [H] [I] [J] [K] [L] [M] [N] [O] [P] [Q] [R] [S] [T] [U] [V] [W] [X] [Y] [Z]

 

 

 

  

(S)-PPHT hydrochloride

(S)-N-0434

 

CAS 159795-62-7 (HCl)

129389-79-0 (free base)

C21H27NO.HCl  MW 345.91

Purity: >98%, 98%ee

 

 

 

 

Ordering Information:

 

Cat. No. Axon 1037

 

Qty1: 5 mg

 

Qty2: 25 mg

 

Qty3: on request

 

Send enquiry to: order@axonmedchem.com

or by fax to: +31-50-3600390.

Contact us for our product range and services.

Biological Activity:

 

(S)-enantiomer of PPHT (Axon 1035), a very potent and specific D2 agonist. 

 

References: online ref 1, 2, 3

 

Van der Weide, J. et al., , Pharmacological profiles of three new, potent and selective dopamine receptor agonists: N-0434, N-0437 and N-0734. Eur. J. Pharmacol.125, 273-282, (1986).

 

Seeman, P., et al., Dopamine D2 receptor binding sites for agonists. A tetrahedral model. Mol. Pharmacol.28, 391, (1985).

 

 

Chemical Name: (S)-2-(N-Phenethyl-N-propyl)amino-5-hydroxytetralin hydrochloride

 

(S)-PPHT | D2 agonist | Axon Medchem | Axon 1037 | (S)-N-0434

axonmedchem.com © 2011

 

Axon Ligands TM

Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.