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Axon Ligands (TM) - alphabetic: [A] [B] [C] [D] [E] [F] [G] [H] [I] [J] [K] [L] [M] [N] [O] [P] [Q] [R] [S] [T] [U] [V] [W] [X] [Y] [Z]

 

 

 

  

8-Hydroxy-DPAT hydrobromide

8-OH-DPAT

 

 

CAS 76135-31-4 (HBr)

78950-78-4 (free base)

C16H25NO.HBr  MW 328.29

Purity: 99%

 

 

 

 

Ordering Information:

 

Cat. No. Axon 1015     Prime Source

 

Qty1: 10 mg / €55  $72

 

Qty2: 50 mg / €185  $241

 

Qty3: 1000 mg / €1650  $2145

 

Send enquiry to: order@axonmedchem.com

or by fax to: +31-50-3600390.

 

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Biological Activity:

 

Standard selective 5-HT1A receptor agonist.

 

References: online ref 1, 2

 

Yoshitake and Kehr. Differential effects of (R)-, (R, S)- and (S)-8-hydroxy-2-(di-n-propylamino)tetralin on hippocampal serotonin release and induction of hypothermia in awake rats. Life Sci. 2004, 74, 2865.


Cornfield, et al. Intrinsic activity of enantiomers of 8-hydroxy-2-(di-n-propylamino)tetralin and its analogs at 5-hydroxytryptamine1A receptors that are negatively coupled to adenylate cyclase. Mol. Pharmacol. 1991, 39, 780.

 

 

 

 

 

Chemical Name: 2-Dipropylamino-8-hydroxy-1,2,3,4-tetrahydro naphthalene hydrobromide or 8-Hydroxy-2-(di-n-propylamino)tetralin hydrobromide

 

8-Hydroxy-DPAT | 5-HT1A agonist | Axon Medchem | Axon 1015 | 8-OH-DPAT

axonmedchem.com © 2011

 

Axon 5-HT1A Ligands: e.g.

8-OH-DPAT | 5-HT1A agonist

(+)-8-OH-DPAT | 5-HT1A agonist

(-)-NPPCC | 5-HT1A agonist

S 14506 | 5-HT1A agonist

Desmethyl S14506

U 92016A | 5-HT1A agonist

LY 426965 | 5-HT1A antagonist

p-MPPF | 5-HT1A antagonist

p-MPPI | 5-HT1A antagonist

WAY 100135 | 5-HT1A antagonist

(S)-WAY100135 | 5-HT1A antag.

WAY 100635 | 5-HT1A antagonist

DWAY | 5-HT1A antagonist

FWAY | 5-HT1A antagonist

 

Axon 5-HT1B/1D Ligands: e.g.

CGS 12066B | 5-HT1B agonist 

Sumatriptan | 5-HT1B/1D agonist

GR 127935 | 5-HT1B/1D antagonist

GMC 2-29 | 5-HT1B/1D antagonist

GMC 3-15 | 5-HT1B/1D antagonist

GMC 15-27 | 5-HT1B/1D antag.

SB 216641 | 5-HT1B antagonist

LY 393558 | SRI, 5-HT1B/1D antag

 

Axon 5-HT1F Ligands:

LY 334370 | 5-HT1F agonist