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(S)-(-)-7-Hydroxyl-DPAT hydrobromide

(S)-7-OH-DPAT

 

 

CAS 82730-73-2 (free base)

C16H25NO.HBr MW 328.29

Purity: >98%, >98%ee

 

 

 

 

Ordering Information:

 

Cat. No. Axon 1014

 

Qty1:  5 mg / €115  $150

 

Qty2: 25 mg / €345  $449

 

Qty3: on request

 

Send enquiry to: order@axonmedchem.com

or by fax to: +31-50-3600390.

 

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Biological Activity:

 

D3 dopamine receptor agonist; less active enantiomer of 7-OH-DPAT (Axon 1012), in comparison with (R)-(+)-7-OH-DPAT (Axon 1013).

 

References:online 1, 2, 3

 

G Damsma et al. Pharmacological aspects of R-(+)-7-OH-DPAT, a putative dopamine D3 ligand. Eur. J. Pharmacol. 1993, 249, R9-R10.

 

LM Pritchard et al. 7-OH-DPAT and PD 128907 Selectively Activate the D3 Dopamine Receptor in a Novel Environment. Neuropsychopharmacology 2003, 28, 100–107.

 

Seeman and Van Tol. Dopamine receptor pharmacology. TiPS 1994, 15, 264.

 

 

Chemical Name: (S)-(-)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol hydrobromide

 

(S)-(-)-7-hydroxy-DPAT | D3 agonist | Axon Medchem | Axon 1014

axonmedchem.com © 2011

 

DRD3 related ligands: e.g.

 

7-hydroxy-DPAT | D3 agonist

(R)-(+)-7-OH-DPAT | D3 agonist

(±)-PD 128907 | D3 agonist

(+)-PD 128907 | D3 agonist

ST 198 | D3 antagonist

U 99194 | D3 antagonist

GR 103691 | D3 antagonist

 

 

Axon Ligands TM

Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.