Axon Ligands (TM) - alphabetic: [A] [B] [C] [D] [E] [F] [G] [H] [I] [J] [K] [L] [M] [N] [O] [P] [Q] [R] [S] [T] [U] [V] [W] [X] [Y] [Z]

5-Hydroxyl-DPAT hydrobromide

5-OH-DPAT

CAS 71787-83-2 (HBr)

68593-96-4 (free base)

C16H25NO.HBr  MW 328.29

Purity: 99%

Ordering Information:

Cat. No. Axon 1006

Qty1: 10 mg / inquire

Qty2: 50 mg / inquire

Qty3: on request

Send enquiry to: order@axonmedchem.com

or by fax to: +31-50-3600390.

Contact us for our product range and services.

Biological Activity:   Potent and selective dopamine (DA) D2-receptor agonist; [11C]5-OH-DPAT is being developed as a PET agent for the high-affinity state of D2/3 receptors.   References:online 1, 2, 3, 4, 5   A Karlsson et al. (R)- and (S)-5-hydroxy-2-(dipropylamino)tetralin (5-OH DPAT): Assessment of optical purities and dopaminergic activities. Chirality. 1989-1995, 2(2), 90-95.   AK Nugroho et al. Transdermal iontophoresis of the dopamine agonist 5-OH-DPAT in human skin in vitro. J. Controlled Release 2005, 103(2), 393-403.   B Shi et al. Radiosynthesis and in vitro evaluation of 2-(N-alkyl-N-1'-11C-propyl)amino-5-hydroxytetralin analogs as high affinity agonists for dopamine D-2 receptors.Nucl Med Biol. 1999, 26(7), 725-35. (PubMed)   J Mukherjee et al. In vitro and in vivo evaluation of the binding of the dopamine D2 receptor agonist (11)C-(R,S)-5-hydroxy-2-(di-n-propylamino)tetralin in rodents and nonhuman primate.Synapse. 2000, 37(1), 64-70. (PubMed)     Chemical Name: 6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol hydrobromide

5-hydroxy-DPAT | D2 agonist | Axon Medchem | Axon 1006 | 5-OH-DPAT

axonmedchem.com © 2011

Axon Ligands ^TM

Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.